Report of a Case of Cerebral Malaria

aft *S no^e<^ that the second slide, 8 hours inf .treatment had begun, showed a heavier Action than the first one. the first slide showed two crescents per field, ^ while the quinine was being given and the rings being destroyed, the number of crescents steadily increased to fourteen per field. Pamaquin was then given, and in four days the slide was quite clear. Lumbar puncture, towards the end of the first 24 hours and again during the third day, showed that the C.S.F. was under normal pressure, so that in this instance there was no oedema of the brain. The fundi were normal. The long period during which the patient remained unconscious and the abnormal neurological signs on the second day suggest that, had treatment been more leisurely, recovery would not have taken place. The rectal temperature remained 102?F. to 103 ?F. during the period of unconsciousness, five days, due in part, during the last two days, to pulmonary involvement for which M&B 693 was given, at first intravenously and later by mouth. Adequate intravenous glucose-saline was given until he was able to swallow.